Reinhard W. Koster

Reinhard is now at the
Institute of Developmental Genetics

The in vivo analysis of the cellular and molecular mechanisms of neuronal migration is the major interest of my work. Toward this the almost transparent zebrafish embryo is being used to elucidate the migratory pathways and migratory behaviors of migrating neuronal precursors cells in the developing cerebellum.

By developing transient and stable transgenic strategies for simultaneous in vivo imaging and molecular interference of individual neuronal precursors the molecular basis of these migratory behaviors and pathfinding skills are being addressed.

Fish larvae have an immense potential to regenerate parts of the central nervous system. The cellular and molecular regeneration processes are being studied directly inside the larval cerebellum with major emphasis on migratory events.

My second research focus represents the in vivo quantification of intracardiac blood flow and its influence on cardiac morphogenesis during embryonic development.


Recent Publications :
Tracing transgene expressing cells
Imaging neuronal migration in vivo
Intracardiac fluid forces influence embryonic cardiogenesis